Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus

Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse s...

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Bibliografiske detaljer
Udgivet i:Front Neuroanat
Main Authors: Haddad-Tóvolli, Roberta, Paul, Fabian A., Zhang, Yuanfeng, Zhou, Xunlei, Theil, Thomas, Puelles, Luis, Blaess, Sandra, Alvarez-Bolado, Gonzalo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Neuroanatomy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373379/
https://ncbi.nlm.nih.gov/pubmed/25859185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2015.00034
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