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Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus
Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse s...
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| Publié dans: | Front Neuroanat |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373379/ https://ncbi.nlm.nih.gov/pubmed/25859185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2015.00034 |
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