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Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus

Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse s...

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Détails bibliographiques
Publié dans:Front Neuroanat
Auteurs principaux: Haddad-Tóvolli, Roberta, Paul, Fabian A., Zhang, Yuanfeng, Zhou, Xunlei, Theil, Thomas, Puelles, Luis, Blaess, Sandra, Alvarez-Bolado, Gonzalo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373379/
https://ncbi.nlm.nih.gov/pubmed/25859185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2015.00034
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