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TGFβ and Wnt in Cardiac Outflow Tract Defects in Offspring of Diabetic Pregnancies
BACKGROUND: Diabetes mellitus in pregnancy causes defects in infant heart, includingthe outflow tracts (OFTs). Development of the aorta and pulmonary artery, which are derived from the common OFT in the embryo, is regulated by the transforming growth factor β (TGFβ) and Wnt families, and can be pert...
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| Veröffentlicht in: | Birth Defects Res B Dev Reprod Toxicol |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372991/ https://ncbi.nlm.nih.gov/pubmed/25231192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21120 |
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