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TGFβ and Wnt in Cardiac Outflow Tract Defects in Offspring of Diabetic Pregnancies

BACKGROUND: Diabetes mellitus in pregnancy causes defects in infant heart, includingthe outflow tracts (OFTs). Development of the aorta and pulmonary artery, which are derived from the common OFT in the embryo, is regulated by the transforming growth factor β (TGFβ) and Wnt families, and can be pert...

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Detalhes bibliográficos
Publicado no:Birth Defects Res B Dev Reprod Toxicol
Autor principal: Zhao, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372991/
https://ncbi.nlm.nih.gov/pubmed/25231192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21120
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