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TGFβ and Wnt in Cardiac Outflow Tract Defects in Offspring of Diabetic Pregnancies

BACKGROUND: Diabetes mellitus in pregnancy causes defects in infant heart, includingthe outflow tracts (OFTs). Development of the aorta and pulmonary artery, which are derived from the common OFT in the embryo, is regulated by the transforming growth factor β (TGFβ) and Wnt families, and can be pert...

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Vydáno v:Birth Defects Res B Dev Reprod Toxicol
Hlavní autor: Zhao, Zhiyong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372991/
https://ncbi.nlm.nih.gov/pubmed/25231192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21120
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