Effect of In Vitro Syncytium Formation on the Severity of Human Metapneumovirus Disease in a Murine Model

Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infections (ARTI) in children, elderly individuals and immunocompromised patients. In vitro, different HMPV strains can induce variable cytopathic effects ranging from large multinucleated syncytia to focal cell rounding....

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Bibliographic Details
Published in:PLoS One
Main Authors: Aerts, Laetitia, Cavanagh, Marie-Hélène, Dubois, Julia, Carbonneau, Julie, Rhéaume, Chantal, Lavigne, Sophie, Couture, Christian, Hamelin, Marie-Ève, Boivin, Guy
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372586/
https://ncbi.nlm.nih.gov/pubmed/25803584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120283
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