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Effect of In Vitro Syncytium Formation on the Severity of Human Metapneumovirus Disease in a Murine Model

Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infections (ARTI) in children, elderly individuals and immunocompromised patients. In vitro, different HMPV strains can induce variable cytopathic effects ranging from large multinucleated syncytia to focal cell rounding....

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Vydáno v:PLoS One
Hlavní autoři: Aerts, Laetitia, Cavanagh, Marie-Hélène, Dubois, Julia, Carbonneau, Julie, Rhéaume, Chantal, Lavigne, Sophie, Couture, Christian, Hamelin, Marie-Ève, Boivin, Guy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372586/
https://ncbi.nlm.nih.gov/pubmed/25803584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120283
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