Integrating Solid-State NMR and Computational Modeling to Investigate the Structure and Dynamics of Membrane-Associated Ghrelin

The peptide hormone ghrelin activates the growth hormone secretagogue receptor 1a, also known as the ghrelin receptor. This 28-residue peptide is acylated at Ser3 and is the only peptide hormone in the human body that is lipid-modified by an octanoyl group. Little is known about the structure and dy...

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Publicat a:PLoS One
Autors principals: Vortmeier, Gerrit, DeLuca, Stephanie H., Els-Heindl, Sylvia, Chollet, Constance, Scheidt, Holger A., Beck-Sickinger, Annette G., Meiler, Jens, Huster, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372444/
https://ncbi.nlm.nih.gov/pubmed/25803439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122444
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