Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9

ZFN, TALENs and CRISPR/Cas9 system have been used to generate point mutations and large fragment deletions and insertions in genomic modifications. CRISPR/Cas9 system is the most flexible and fast developing technology that has been extensively used to make mutations in all kinds of organisms. Howev...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Zhang, Luqing, Jia, Ruirui, Palange, Norberto J., Satheka, Achim Cchitvsanzwhoh, Togo, Jacques, An, Yao, Humphrey, Mabwi, Ban, Luying, Ji, Yan, Jin, Honghong, Feng, Xuechao, Zheng, Yaowu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372442/
https://ncbi.nlm.nih.gov/pubmed/25803037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120396
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