Cytotoxic Helix-Rich Oligomer Formation by Melittin and Pancreatic Polypeptide

Conversion of amyloid fibrils by many peptides/proteins involves cytotoxic helix-rich oligomers. However, their toxicity and biophysical studies remain largely unknown due to their highly dynamic nature. To address this, we chose two helical peptides (melittin, Mel and pancreatic polypeptide, PP) an...

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Vydáno v:PLoS One
Hlavní autoři: Singh, Pradeep K., Ghosh, Dhiman, Tewari, Debanjan, Mohite, Ganesh M., Carvalho, Edmund, Jha, Narendra Nath, Jacob, Reeba S., Sahay, Shruti, Banerjee, Rinti, Bera, Amal K., Maji, Samir K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372375/
https://ncbi.nlm.nih.gov/pubmed/25803428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120346
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