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Cytotoxic Helix-Rich Oligomer Formation by Melittin and Pancreatic Polypeptide

Conversion of amyloid fibrils by many peptides/proteins involves cytotoxic helix-rich oligomers. However, their toxicity and biophysical studies remain largely unknown due to their highly dynamic nature. To address this, we chose two helical peptides (melittin, Mel and pancreatic polypeptide, PP) an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Singh, Pradeep K., Ghosh, Dhiman, Tewari, Debanjan, Mohite, Ganesh M., Carvalho, Edmund, Jha, Narendra Nath, Jacob, Reeba S., Sahay, Shruti, Banerjee, Rinti, Bera, Amal K., Maji, Samir K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372375/
https://ncbi.nlm.nih.gov/pubmed/25803428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120346
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