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Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
The small number of hematopoietic stem and progenitor cells in cord blood units limits their widespread use in human transplant protocols. We identified a family of chemically related small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hema...
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| Publié dans: | Science |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372335/ https://ncbi.nlm.nih.gov/pubmed/25237102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256337 |
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