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Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy

Treatment of melanoma cells by sodium arsenite or statins (simvastatin and lovastatin) dramatically modified activities of the main cell signaling pathways resulting in the induction of heme oxygenase-1 (HO-1) and in a downregulation of cyclooxygenase-2 (COX-2) protein levels. Through heme degradati...

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Bibliografiske detaljer
Udgivet i:Apoptosis
Main Authors: Ivanov, Vladimir N., Hei, Tom K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372201/
https://ncbi.nlm.nih.gov/pubmed/21910007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0649-2
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