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Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy

Treatment of melanoma cells by sodium arsenite or statins (simvastatin and lovastatin) dramatically modified activities of the main cell signaling pathways resulting in the induction of heme oxygenase-1 (HO-1) and in a downregulation of cyclooxygenase-2 (COX-2) protein levels. Through heme degradati...

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Vydáno v:Apoptosis
Hlavní autoři: Ivanov, Vladimir N., Hei, Tom K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372201/
https://ncbi.nlm.nih.gov/pubmed/21910007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-011-0649-2
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