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Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells

Most human melanomas express Fas receptor on the cell surface, and treatment with exogenous Fas Ligand (FasL) efficiently induces apoptosis of these cells. In contrast, endogenous surface expression of FasL is suppressed in Fas-positive melanomas. We report here the use of a combination of sodium ar...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Ivanov, Vladimir N., Hei, Tom K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376328/
https://ncbi.nlm.nih.gov/pubmed/16487513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2006.01.003
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