HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

[Image: see text] We examined the effects of isoform-specific histone deacetylase (HDAC) inhibitors on β-catenin posttranslational modifications in neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs). β-catenin is a multifunctional protein with important roles in...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Iaconelli, Jonathan, Huang, Joanne H., Berkovitch, Shaunna S., Chattopadhyay, Shrikanta, Mazitschek, Ralph, Schreiber, Stuart L., Haggarty, Stephen J., Karmacharya, Rakesh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372110/
https://ncbi.nlm.nih.gov/pubmed/25546293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500838r
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