The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer

BACKGROUND: The human genome encodes many long non-coding RNAs (lncRNAs). However, their biological functions, molecular mechanisms, and the prognostic value associated with pancreatic ductal adenocarcinoma (PDAC) remain to be elucidated. Here, we identify a fundamental role for the lncRNA HOXA tran...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Li, Zhihua, Zhao, Xiaohui, Zhou, Yu, Liu, Yimin, Zhou, Quanbo, Ye, Huilin, Wang, YinXue, Zeng, Jinlong, Song, Yadong, Gao, Wenchao, Zheng, ShangYou, Zhuang, Baoxiong, Chen, Huimou, Li, Wenzhu, Li, Haigang, Li, Haifeng, Fu, Zhiqiang, Chen, Rufu
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372045/
https://ncbi.nlm.nih.gov/pubmed/25889214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0442-z
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