Nalaganje...

Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4

The gain-of-function mutant p53 (mtp53) transcriptome has been studied, but, to date, no detailed analysis of the mtp53-associated proteome has been described. We coupled cell fractionation with stable isotope labeling with amino acids in cell culture (SILAC) and inducible knockdown of endogenous mt...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Polotskaia, Alla, Xiao, Gu, Reynoso, Katherine, Martin, Che, Qiu, Wei-Gang, Hendrickson, Ronald C., Bargonetti, Jill
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371979/
https://ncbi.nlm.nih.gov/pubmed/25733866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416318112
Oznake: Označite
Brez oznak, prvi označite!