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Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer
Over 80% of Triple Negative Breast Cancers (TNBC) express mutant p53 (mtp53) and some contain oncogenic gain-of-function (GOF) p53. We previously reported that GOF mtp53 R273H upregulates the chromatin association of Mini Chromosome Maintenance (MCM) proteins MCM2–7 and Poly-ADP-Ribose Polymerase (P...
Gorde:
| Argitaratua izan da: | Cancer Res |
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| Egile Nagusiak: | , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002183/ https://ncbi.nlm.nih.gov/pubmed/31776133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1036 |
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