Loading...

Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer

Over 80% of Triple Negative Breast Cancers (TNBC) express mutant p53 (mtp53) and some contain oncogenic gain-of-function (GOF) p53. We previously reported that GOF mtp53 R273H upregulates the chromatin association of Mini Chromosome Maintenance (MCM) proteins MCM2–7 and Poly-ADP-Ribose Polymerase (P...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Xiao, Gu, Lundine, Devon, Annor, George K., Canar, Jorge, Ellison, Viola, Polotskaia, Alla, Donabedian, Patrick L., Reiner, Thomas, Khramtsova, Galina F., Olopade, Olufunmilayo I., Mazo, Alexander, Bargonetti, Jill
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002183/
https://ncbi.nlm.nih.gov/pubmed/31776133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1036
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!