Llwytho...

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

Diabetes and insulin resistance are associated with altered brain imaging, depression, and increased rates of age-related cognitive impairment. Here we demonstrate that mice with a brain-specific knockout of the insulin receptor (NIRKO mice) exhibit brain mitochondrial dysfunction with reduced mitoc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kleinridders, Andre, Cai, Weikang, Cappellucci, Laura, Ghazarian, Armen, Collins, William R., Vienberg, Sara G., Pothos, Emmanuel N., Kahn, C. Ronald
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371978/
https://ncbi.nlm.nih.gov/pubmed/25733901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500877112
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!