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Lrp4 in osteoblasts suppresses bone formation and promotes osteoclastogenesis and bone resorption
Bone mass is maintained by balanced activity of osteoblasts and osteoclasts. Lrp4 (low-density lipoprotein receptor related protein 4) is a member of the LDL receptor family, whose mutations have been identified in patients with high–bone-mass disorders, such as sclerosteosis and van Buchem diseases...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371963/ https://ncbi.nlm.nih.gov/pubmed/25733894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419714112 |
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