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Lrp4 in osteoblasts suppresses bone formation and promotes osteoclastogenesis and bone resorption

Bone mass is maintained by balanced activity of osteoblasts and osteoclasts. Lrp4 (low-density lipoprotein receptor related protein 4) is a member of the LDL receptor family, whose mutations have been identified in patients with high–bone-mass disorders, such as sclerosteosis and van Buchem diseases...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Xiong, Lei, Jung, Ji-Ung, Wu, Haitao, Xia, Wen-Fang, Pan, Jin-Xiu, Shen, Chengyong, Mei, Lin, Xiong, Wen-Cheng
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371963/
https://ncbi.nlm.nih.gov/pubmed/25733894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419714112
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