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Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy

Assembly and maturation of the human immunodeficiency virus type 1 (HIV-1) are governed by the Gag polyprotein. Here we study the conformation and dynamics of a large HIV-1 Gag fragment comprising the matrix, capsid, spacer peptide 1 and nucleocapsid domains (referred to as ΔGag) by heteronuclear mu...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Deshmukh, Lalit, Ghirlando, Rodolfo, Clore, G. Marius
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371905/
https://ncbi.nlm.nih.gov/pubmed/25713345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501985112
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