Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations.

Two genes have been implicated in leukemias of patients with abnormalities of chromosome 3, band q26: EVI1, which can be activated over long distances by chromosomal rearrangements involving 3q26, and EAP, a ribosomal gene that fuses with AML1 in a therapy-related myelodysplasia patient with a t(3;2...

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Autori principali: Nucifora, G, Begy, C R, Kobayashi, H, Roulston, D, Claxton, D, Pedersen-Bjergaard, J, Parganas, E, Ihle, J N, Rowley, J D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC43711/
https://ncbi.nlm.nih.gov/pubmed/8171026
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