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Influence of Process and Formulation Parameters on Dissolution and Stability Characteristics of Kollidon® VA 64 Hot-Melt Extrudates

The objective of the present study was to investigate the effects of processing variables and formulation factors on the characteristics of hot-melt extrudates containing a copolymer (Kollidon® VA 64). Nifedipine was used as a model drug in all of the extrudates. Differential scanning calorimetry (D...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:AAPS PharmSciTech
Prif Awduron: Maddineni, Sindhuri, Battu, Sunil Kumar, Morott, Joe, Majumdar, Soumyajit, Murthy, S. N., Repka, Michael A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370970/
https://ncbi.nlm.nih.gov/pubmed/25361900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0226-4
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