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DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma

Chimeric antigen receptor (CAR) T cell therapies hold great potential for treating cancers, and new CARs that can target multiple tumor types and have the potential to target non-hematological malignancies are needed. In this study, the tumor recognition ability of a natural killer cell-activating r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Immunol Immunother
Päätekijät: Wu, Ming-Ru, Zhang, Tong, Alcon, Andre, Sentman, Charles L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370794/
https://ncbi.nlm.nih.gov/pubmed/25549845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-014-1648-2
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