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A permutational approach toward protein-DNA recognition.

The cI repressor of bacteriophage 434, known as 434 repressor, binds to 14-bp operator sequences by means of a helix-turn-helix motif. To probe the requirements for selective DNA recognition by this class of DNA binding proteins, as well as to generate new proteins with altered specificities, a libr...

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Detalhes bibliográficos
Main Authors: Huang, L, Sera, T, Schultz, P G
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43704/
https://ncbi.nlm.nih.gov/pubmed/8171021
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