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The leucine zipper symmetrically positions the adjacent basic regions for specific DNA binding.

The bZIP structural motif present in several eukaryotic transcription factors is defined by the leucine zipper, a coiled-coil dimerization interface, and an adjacent basic region that directly interacts with DNA. To examine the functional importance of the highly conserved spacing between the leucin...

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Detalles Bibliográficos
Main Authors: Pu, W T, Struhl, K
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC52201/
https://ncbi.nlm.nih.gov/pubmed/1871104
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