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The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB.

The X gene product encoded by the hepatitis B virus, termed pX, is a promiscuous transactivator of a variety of viral and cellular genes under the control of diverse cis-acting elements. Although pX does not appear to directly bind DNA, pX-responsive elements include the NF-kappa B, AP-1, and CRE (c...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Williams, J S, Andrisani, O M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7731990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3819
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