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Murine model of Hirschsprung-associated enterocolitis. I: Phenotypic characterization with development of a histopathologic grading system
PURPOSE: The aim of the study was to characterize enterocolitis in the Ednrb-null (Ednrb−/−) mouse with aganglionosis of the colon and to develop and validate a semiquantitative histopathologic grading system to assess enterocolitis. METHODS: We isolated colon and ileal specimens of Ednrb−/− and con...
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| Publicado en: | J Pediatr Surg |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4370315/ https://ncbi.nlm.nih.gov/pubmed/20223308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2009.06.009 |
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