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Enterocolitis causes profound lymphoid depletion in endothelin receptor B- and endothelin 3-null mouse models of Hirschsprung-associated enterocolitis

Potentially life-threatening enterocolitis is the most frequent complication in children with colonic aganglionosis (Hirschsprung disease, HSCR), and little is known about the mechanisms leading to enterocolitis. Splenic lymphopenia has been reported in the Endothelin Receptor B (Ednrb)-null mouse m...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Frykman, Philip K., Cheng, Zhi, Wang, Xiao, Dhall, Deepti
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370321/
https://ncbi.nlm.nih.gov/pubmed/25487064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444737
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