Murine model of Hirschsprung-associated enterocolitis II: Surgical correction of aganglionosis does not eliminate enterocolitis

BACKGROUND: Hirschsprung disease (HD) results from aganglionosis of the colon, is linked to acute and chronic enterocolitis (known as Hirschsprung-associated enterocolitis) despite successful corrective surgery, and can lead to bacteremia and even death. The genetic and molecular mechanisms underlyi...

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Pubblicato in:J Pediatr Surg
Autori principali: Zhao, Lifu, Dhall, Deepti, Cheng, Zhi, Wang, Hanlin L., Doherty, Terence M., Bresee, Catherine, Frykman, Philip K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375950/
https://ncbi.nlm.nih.gov/pubmed/20105605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2009.10.035
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