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A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic

Some members of the transient receptor potential (TRP) family of cation channels mediate sensory responses to irritant substances. Although it is well known that TRPA1 channels are activated by pungent compounds found in garlic, onion, mustard and cinnamon extracts, activation of TRPV1 by these extr...

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Vydáno v:Nat Neurosci
Hlavní autoři: Salazar, Héctor, Llorente, Itzel, Jara-Oseguera, Andrés, García-Villegas, Refugio, Munari, Mika, Gordon, Sharona E, Islas, León D, Rosenbaum, Tamara
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370189/
https://ncbi.nlm.nih.gov/pubmed/18297068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2056
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