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A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic

Some members of the transient receptor potential (TRP) family of cation channels mediate sensory responses to irritant substances. Although it is well known that TRPA1 channels are activated by pungent compounds found in garlic, onion, mustard and cinnamon extracts, activation of TRPV1 by these extr...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Salazar, Héctor, Llorente, Itzel, Jara-Oseguera, Andrés, García-Villegas, Refugio, Munari, Mika, Gordon, Sharona E, Islas, León D, Rosenbaum, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370189/
https://ncbi.nlm.nih.gov/pubmed/18297068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2056
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