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Properties of the Inner Pore Region of TRPV1 Channels Revealed by Block with Quaternary Ammoniums

The transient receptor potential vanilloid 1 (TRPV1) nonselective cationic channel is a polymodal receptor that activates in response to a wide variety of stimuli. To date, little structural information about this channel is available. Here, we used quaternary ammonium ions (QAs) of different sizes...

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Autors principals: Jara-Oseguera, Andrés, Llorente, Itzel, Rosenbaum, Tamara, Islas, León D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571972/
https://ncbi.nlm.nih.gov/pubmed/18955595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810051
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