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CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-using HIV-1 Glycoprotein 120()

The innate immune system has been implicated in several neurodegenerative diseases, including human immunodeficiency virus (HIV)-1 associated dementia. Here we show that genetic ablation of CCR5 prevents microglial activation and neuronal damage in a transgenic model of HIV-associated brain injury i...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Maung, Ricky, Hoefer, Melanie M., Sanchez, Ana B., Sejbuk, Natalia E., Medders, Kathryn E., Desai, Maya K., Catalan, Irene C., Dowling, Cari C., de Rozieres, Cyrus M., Garden, Gwenn A., Russo, Rossella, Roberts, Amanda J., Williams, Roy, Kaul, Marcus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370188/
https://ncbi.nlm.nih.gov/pubmed/25031461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302915
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