Antiretrovirals, Methamphetamine, and HIV-1 Envelope Protein gp120 Compromise Neuronal Energy Homeostasis in Association with Various Degrees of Synaptic and Neuritic Damage

HIV-1 infection frequently causes HIV-associated neurocognitive disorders (HAND) despite combination antiretroviral therapy (cART). Evidence is accumulating that components of cART can themselves be neurotoxic upon long-term exposure. In addition, abuse of psychostimulants, such as methamphetamine,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sanchez, Ana B., Varano, Giuseppe P., de Rozieres, Cyrus M., Maung, Ricky, Catalan, Irene C., Dowling, Cari C., Sejbuk, Natalia E., Hoefer, Melanie M., Kaul, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704202/
https://ncbi.nlm.nih.gov/pubmed/26482305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01632-15
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