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Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli
TTP is an anti-inflammatory protein that acts by binding to AREs in its target mRNAs, such as Tnf mRNA, and promoting their deadenylation and decay. TNF released from inflammatory cells can then stimulate gene expression in tissue cells, such as fibroblasts. To determine whether TTP could affect the...
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| Опубликовано в: : | J Leukoc Biol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Leukocyte Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4370050/ https://ncbi.nlm.nih.gov/pubmed/25657290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0214-106R |
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