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Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli

TTP is an anti-inflammatory protein that acts by binding to AREs in its target mRNAs, such as Tnf mRNA, and promoting their deadenylation and decay. TNF released from inflammatory cells can then stimulate gene expression in tissue cells, such as fibroblasts. To determine whether TTP could affect the...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Qiu, Lian-Qun, Lai, Wi S., Bradbury, Alyce, Zeldin, Darryl C., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370050/
https://ncbi.nlm.nih.gov/pubmed/25657290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0214-106R
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