Prolylcarboxypeptidase Independently Activates Plasma Prekallikrein (Fletcher Factor)

Prolylcarboxypeptidase isoform 1 (PRCP1) is capable of regulating numerous autocrines and hormones, such as angiotensin II, angiotensin III, αMSH(1-13), and DesArg(9) bradykinin. It does so by cleaving a C-terminal PRO-X bond. Recent work also indicates that the human PRCP1 activates plasma prekalli...

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Bibliografske podrobnosti
izdano v:Curr Mol Med
Main Authors: Wang, J., Matafonov, A., Madkhali, H., Mahdi, F., Watson, D., Schmaier, A.H., Gailani, D., Shariat-Madar, Z.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369925/
https://ncbi.nlm.nih.gov/pubmed/25324000
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