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Prolylcarboxypeptidase (PRCP) as a new target for obesity treatment

Recently, we serendipitously discovered that mice with the deficiency of the enzyme prolylcarboxypeptidase (PRCP) have elevated α-melanocyte-stimulating hormone (α-MSH) levels which lead to decreased food intake and weight loss. This suggests that PRCP is an endogenous inactivator of α-MSH and an ap...

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Autori principali: Shariat-Madar, B, Kolte, D, Verlangieri, A, Shariat-Madar, Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916657/
https://ncbi.nlm.nih.gov/pubmed/20694162
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