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Influence of a Novel Inhibitor (UM8190) of Prolylcarboxypeptidase (PRCP) on Appetite and Thrombosis

Preclinical pharmacological characterization of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) was investigated. We synthesized and evaluated a library of proline-based analogs as prospective recombinant PRCP (rPRCP) inhibitors and inhibitors of PRCP-dependent prekallikrein (PK) activat...

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Bibliografiska uppgifter
I publikationen:Curr Med Chem
Huvudupphovsmän: Rabey, F. M., Gadepalli, R.S.V.S., Diano, S., Cheng, Q., Tabrizian, T., Gailani, D., Rimoldi, J.M., Shariat-Madar, Z.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367813/
https://ncbi.nlm.nih.gov/pubmed/22664251
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