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Genetic determinants for methotrexate response in juvenile idiopathic arthritis
Juvenile idiopathic arthritis (JIAs) is the most common chronic rheumatic disease of childhood and is an important cause of disability. The folic acid analog methotrexate is the first choice disease-modifying anti-rheumatic drug in this disease, however, 35–45% of patients fail to respond. Molecular...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369651/ https://ncbi.nlm.nih.gov/pubmed/25852556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00052 |
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