Genetic determinants for methotrexate response in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIAs) is the most common chronic rheumatic disease of childhood and is an important cause of disability. The folic acid analog methotrexate is the first choice disease-modifying anti-rheumatic drug in this disease, however, 35–45% of patients fail to respond. Molecular...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Pastore, Serena, Stocco, Gabriele, Favretto, Diego, De Iudicibus, Sara, Taddio, Andrea, d’Adamo, Pio, Malusà, Noelia, Addobbati, Riccardo, Decorti, Giuliana, Lepore, Loredana, Ventura, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369651/
https://ncbi.nlm.nih.gov/pubmed/25852556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00052
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