Genetic determinants for methotrexate response in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIAs) is the most common chronic rheumatic disease of childhood and is an important cause of disability. The folic acid analog methotrexate is the first choice disease-modifying anti-rheumatic drug in this disease, however, 35–45% of patients fail to respond. Molecular...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Pastore, Serena, Stocco, Gabriele, Favretto, Diego, De Iudicibus, Sara, Taddio, Andrea, d’Adamo, Pio, Malusà, Noelia, Addobbati, Riccardo, Decorti, Giuliana, Lepore, Loredana, Ventura, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369651/
https://ncbi.nlm.nih.gov/pubmed/25852556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00052
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