Genetic determinants for methotrexate response in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIAs) is the most common chronic rheumatic disease of childhood and is an important cause of disability. The folic acid analog methotrexate is the first choice disease-modifying anti-rheumatic drug in this disease, however, 35–45% of patients fail to respond. Molecular...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Pastore, Serena, Stocco, Gabriele, Favretto, Diego, De Iudicibus, Sara, Taddio, Andrea, d’Adamo, Pio, Malusà, Noelia, Addobbati, Riccardo, Decorti, Giuliana, Lepore, Loredana, Ventura, Alessandro
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369651/
https://ncbi.nlm.nih.gov/pubmed/25852556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00052
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