Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma

Medulloblastoma (MB) is a highly malignant brain tumor that occurs primarily in children. Although surgery, radiation and high-dose chemotherapy have led to increased survival, many MB patients still die from their disease, and patients who survive suffer severe long-term side effects as a consequen...

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Veröffentlicht in:Oncogene
Hauptverfasser: Brun, Sonja N., Markant, Shirley L., Esparza, Lourdes A., Garcia, Guillermina, Terry, David, Huang, Jen-Ming, Pavlyukov, Marat S., Li, Xiao-Nan, Grant, Gerald A., Crawford, John R., Levy, Michael L., Conway, Edward M., Smith, Layton H., Nakano, Ichiro, Berezov, Alan, Greene, Mark I., Wang, Qiang, Wechsler-Reya, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369477/
https://ncbi.nlm.nih.gov/pubmed/25241898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.304
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