Targeting Sonic Hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-Like Kinases

Medulloblastoma (MB) is the most common malignant brain tumor in children. While aggressive surgery, radiation, and chemotherapy have improved outcomes, survivors suffer severe long-term side effects, and many patients still succumb to their disease. For patients whose tumors are driven by mutations...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Markant, Shirley L., Esparza, Lourdes Adriana, Sun, Jesse, Barton, Kelly L., McCoig, Lisa M., Grant, Gerald A., Crawford, John R., Levy, Michael L., Northcott, Paul A., Shih, David, Remke, Marc, Taylor, Michael D., Wechsler-Reya, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800039/
https://ncbi.nlm.nih.gov/pubmed/24067506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4258
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge