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Structure-Activity Relationships of Somatostatin Analogs in the Rabbit Ileum and the Rat Colon

Somatostatin increases absorption of electrolytes and inhibits diarrhea in patients with endocrine tumors and short bowel syndrome. In an attempt to develop a gut-specific somatostatin analog, each amino acid in the somatostatin molecule was replaced with L-alanine, deleted, or substituted with its...

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Autors principals: Rosenthal, Linda E., Yamashiro, Darrell J., Rivier, Jean, Vale, Wylie, Brown, Marvin, Dharmsathaphorn, Kiertisin
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC436941/
https://ncbi.nlm.nih.gov/pubmed/6131906
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