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Structure-Activity Relationships of Somatostatin Analogs in the Rabbit Ileum and the Rat Colon

Somatostatin increases absorption of electrolytes and inhibits diarrhea in patients with endocrine tumors and short bowel syndrome. In an attempt to develop a gut-specific somatostatin analog, each amino acid in the somatostatin molecule was replaced with L-alanine, deleted, or substituted with its...

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Detalhes bibliográficos
Main Authors: Rosenthal, Linda E., Yamashiro, Darrell J., Rivier, Jean, Vale, Wylie, Brown, Marvin, Dharmsathaphorn, Kiertisin
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC436941/
https://ncbi.nlm.nih.gov/pubmed/6131906
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