Switch from fetal to adult hemoglobin is associated with a change in progenitor cell population.

To examine the switch from fetal to adult hemoglobin at the cellular level, erythroid progenitor cells from newborn infants and adults were cultured in methyl cellulose with erythropoietin. Individual erythroid colonies were labeled with [3H]leucine at various times, and globin synthesis patterns ex...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Weinberg, R S, Goldberg, J D, Schofield, J M, Lenes, A L, Styczynski, R, Alter, B P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436935/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6187772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110832
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