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RhoC is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer
RhoGDI2 (ARHGDIB) suppresses metastasis in a variety of cancers but the mechanism is unclear; thus, hampering development of human therapeutics. RhoGDI2 is a guanine nucleotide dissociation inhibitor (GDI) for the Rho family of GTPases thought to primarily bind to Rac1; however, Rac1 activation was...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369172/ https://ncbi.nlm.nih.gov/pubmed/25516960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0420 |
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