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A Vascular Model of Tsc1 Deficiency Accelerates Renal Tumor Formation with Accompanying Hemangiosarcomas

Tuberous Sclerosis Complex (TSC) is an autosomal disease caused by inactivating mutations in either of the tumor suppressor genes TSC1 or TSC2. TSC-associated tumor growth is present in multiple tissues and organs including brain, kidney, liver, heart, lungs, and skin. In the kidney, TSC angiomyolip...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Leech, Jarrett D., Lammers, Stephen H.T., Goldman, Sam, Auricchio, Neil, Bronson, Roderick T., Kwiatkowski, David J., Sahin, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369160/
https://ncbi.nlm.nih.gov/pubmed/25548102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0178
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