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A novel mouse model of hemangiopericytoma due to loss of Tsc2

Hemangiopericytoma (HPC) is a rare vascular tumor, which is thought to originate from pericytes. However, no direct evidence for the cell of origin has been found, and the mechanism of HPC tumorigenesis is poorly understood. Here we report that loss of the tumor suppressor gene Tsc2 in pericytes usi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Du, Heng, Dreier, John R, Zarei, Mahsa, Wu, Chin-Lee, Bronson, Roderick W, Kwiatkowski, David J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276833/
https://ncbi.nlm.nih.gov/pubmed/30124871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy289
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