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A novel mouse model of hemangiopericytoma due to loss of Tsc2

Hemangiopericytoma (HPC) is a rare vascular tumor, which is thought to originate from pericytes. However, no direct evidence for the cell of origin has been found, and the mechanism of HPC tumorigenesis is poorly understood. Here we report that loss of the tumor suppressor gene Tsc2 in pericytes usi...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Du, Heng, Dreier, John R, Zarei, Mahsa, Wu, Chin-Lee, Bronson, Roderick W, Kwiatkowski, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276833/
https://ncbi.nlm.nih.gov/pubmed/30124871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy289
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